Kaposi's Sarcoma - An Update of Management
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چکیده
Kaposi ' s sarcoma (KS) i s a mul t i focal angioproliferative disease characterised by transdifferentiation of human herpes virus type 8 (HHV-8) infected endothelial cells into spindle-shaped cells, followed by cytokine-dependent transformation, proliferation, neovascularisation and inflammatory cell infiltration. Trans-differentiation is the conversion of differentiated cells either morphologically or functionally, or both.
منابع مشابه
Steroid Induced Kaposi's Sarcoma in an HIV Negative Patient
Kaposi's sarcoma is one of malignancies that is most seen in HIV positive or immunocompromised patients. Kaposi's sarcoma typically involves the skin. We present a HIV negative, 31-year-old Iranian woman from Tehran with Kaposi's sarcoma associated with corticosteroid use.
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Fibroepithelial polyps, also named as soft warts, skin tags, or acrochordons, are common benign lesions that may occur on trunk or exterimities. Its association with infectious agents is unclear. Herein, We report a case of extensive fibroepithelial -like polyps on the foot of an AIDS patient following radiotherapy for Kaposi's sarcoma.
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Immunosuppression is known to be associated with increased rate of malignancies and widespread dermatophytosis in the patients with sezary syndrome and this may account for the occurrence of Kaposi’s sarcoma and generalized dermatophytosis in patients in this report. Herein, we report a 58-year-old farmer man, who admitted with two months history of severely pruritic skin lesions, which p...
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Background: In the Mediterranean region , Kaposi's sarcoma (KS) has a high prevalence especially in patients with AIDS. Iran is located close to the Mediterranean region and the HIV prevalence is increasing in our country . In some stages, Kaposi's sarcoma is morphologically similar to other vascular tumors. Owing to the presence of human herpesvirus 8 (HHV-8) in all cases of Kaposi's sarcoma ,...
متن کاملKaposi's sarcoma in the era of HAART-an update on mechanisms, diagnostics and treatment.
Kaposi's Sarcoma (KS) signified the AIDS epidemic in the 1980's and led to the discovery of the eighth human herpesvirus, KS-associated herpesvirus (KSHV), as the causative agent for this disease. Today we know a lot about KSHV and can begin to understand, diagnose and treat KS as a viral disease rather than another sarcoma.
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